How stem cells remember their past
نویسندگان
چکیده
Somatic stem cells are required for tissue development, homeostasis, and repair. Recent data suggested that previous biographical experiences of individual influence their behavior in the context formation govern cell responses to external stimuli. Here we provide a concise review how cell's biography, example, rounds divisions or age-dependent accumulation cellular damage, is remembered affect segregation components, thus guiding vertebrate cells. Further, suggest future directions research may help unravel molecular underpinnings past guide behavior.
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2021
ISSN: ['1879-0410', '0955-0674']
DOI: https://doi.org/10.1016/j.ceb.2020.12.008